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在感染人类免疫缺陷病毒的马拉维成年人中,血吸虫病不会导致非伤寒沙门氏菌菌血症的死亡或复发。

Schistosomiasis does not contribute to death or recurrence of nontyphoid Salmonella bacteremia in human immunodeficiency virus-infected Malawian adults.

作者信息

Gordon Melita A, Zijlstra Eduard E, Naus Cynthia W A, Visser Leo G, Molyneux Malcolm E, van Lieshout Lisette

机构信息

Wellcome Trust Laboratories, Malawi-Liverpool-Wellcome Trust Clinical Research Programme, Chichiri, Malawi.

出版信息

Clin Infect Dis. 2003 Dec 15;37(12):e177-9. doi: 10.1086/379828. Epub 2003 Nov 19.

Abstract

Nontyphoid Salmonella (NTS) bacteremia has a very high mortality and recurrence rate among human immunodeficiency virus (HIV)-infected Malawian adults. Concurrent schistosomal infection might cause persistence of NTS infection and poor response to antibiotic therapy. Therefore, we tested serum samples for Schistosoma-specific circulating anodic antigen to diagnose coinfection with schistosomiasis among consecutive HIV-positive adults with NTS bacteremia. The results suggest that active schistosomiasis is not associated with adverse outcome of NTS bacteremia in this population, in contrast to other groups.

摘要

非伤寒沙门氏菌(NTS)菌血症在感染人类免疫缺陷病毒(HIV)的马拉维成年人中具有非常高的死亡率和复发率。同时感染血吸虫可能导致NTS感染持续存在,并对抗生素治疗反应不佳。因此,我们检测了血清样本中的血吸虫特异性循环阳极抗原,以诊断连续患有NTS菌血症的HIV阳性成年人中是否合并感染血吸虫病。结果表明,与其他群体不同,在该人群中,活动性血吸虫病与NTS菌血症的不良结局无关。

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