Ramanathan G, Yu C, Osei E, Nicolaides K H
Harris Birthright Research Centre for Fetal Medicine, King's College Hospital Medical School, London, UK.
Ultrasound Obstet Gynecol. 2003 Dec;22(6):598-603. doi: 10.1002/uog.913.
To examine the potential value of routine measurement of cervical length in singleton low-risk pregnancies at 37 weeks of gestation in the prediction of onset and outcome of labor.
Cervical length was measured by transvaginal sonography at 37 weeks in 1571 singleton low-risk pregnancies. Outcome measures were gestation at spontaneous onset of labor, post-term delivery, duration of labor and mode of delivery.
The median cervical length at 37 weeks was 30 mm and there was a significant association between cervical length and gestation at delivery, which increased from a mean of 38 weeks for cervical length of 10 mm to 41 weeks for cervical length of 35 mm. The incidence of delivery after 40 weeks and 10 days was 296 (18.8%) and the incidence increased with cervical length at 37 weeks from 0% to 6%, 35% and 68% for respective cervical lengths of < 20, 21-30, 31-40 and 41-50 mm. In the pregnancies with spontaneous onset of labor the incidence of Cesarean section for failure to progress increased from 3.6% to 6.0%, 6.4% and 11.8% for cervical lengths of < 20, 21-30, 31-40 and 41-50 mm, respectively. In the pregnancies requiring induction for post-term the incidence of Cesarean section for failed induction or failure to progress increased from 7.5% to 20.1% to 25.0% for cervical lengths of 21-30, 31-40 and 41-50 mm, respectively.
Measurement of cervical length at 37 weeks can define the likelihood of spontaneous delivery before 40 weeks and 10 days and the risk of Cesarean section in those requiring induction for prolonged pregnancy.
探讨妊娠37周时单胎低风险妊娠常规测量宫颈长度对预测分娩发动及结局的潜在价值。
对1571例妊娠37周的单胎低风险妊娠孕妇经阴道超声测量宫颈长度。观察指标包括自然发动分娩的孕周、过期产、产程及分娩方式。
妊娠37周时宫颈长度中位数为30mm,宫颈长度与分娩孕周之间存在显著关联,宫颈长度为10mm时平均分娩孕周为38周,宫颈长度为35mm时平均分娩孕周增至41周。40周零10天后分娩的发生率为296例(18.8%),且随着妊娠37周时宫颈长度的增加,发生率从0%增至6%、35%和68%,宫颈长度分别<20mm、21 - 30mm、31 - 40mm和41 - 50mm。自然发动分娩的孕妇中,宫颈长度<20mm、21 - 30mm、31 - 40mm和41 - 50mm时,因产程无进展而行剖宫产的发生率分别从3.6%增至6.0%、6.4%和11.8%。对于过期妊娠需引产的孕妇,宫颈长度为21 - 30mm、31 - 40mm和41 - 50mm时,因引产失败或产程无进展而行剖宫产的发生率分别从7.5%增至20.1%和25.0%。
妊娠37周时测量宫颈长度可明确40周零10天前自然分娩的可能性以及延长妊娠需引产者行剖宫产的风险。