Department of Obstetrics & Gynecology, R.G. Kar Medical College, Kolkata, India.
Department of Radiology, R.G. Kar Medical College, Kolkata, India.
Indian J Med Res. 2017 Oct;146(4):498-504. doi: 10.4103/ijmr.IJMR_881_15.
BACKGROUND & OBJECTIVES: Data on serial cervical length (CL) measurements in pregnancy at term to predict spontaneous labour onset are scarce and conflicting. This study was conducted to observe CL changes preceding spontaneous onset of labour, by serial transvaginal sonography (TVS) and transabdominal sonography (TAS), in nulliparous Indian women near term.
Only nulliparous women with a singleton foetus in cephalic presentation and who confirmed their gestational age were recruited. Sonographic CL measurements were taken at weekly intervals from 36 wk gestation onwards by a single ultrasonologist. Transabdominal and transvaginal measurements were undertaken using the suitable transducer probes with the women in the supine position.
A total of 104 women with spontaneous onset of labour were evaluated. There was substantial variation in CL measurements, both by TVS and by TAS, from 36 to 40 wk gestation, although the two sets of measurements correlated closely. Mean CL changed significantly over the last three weeks before delivery. However, only one-third of the women showed CL change of >5 mm per week in the last three weeks. There was poor correlation between gestational age at delivery and the last measured CL, either by TVS or TAS. Length >3.1 mm, measured by TVS at 38 wk gestation, predicted post-dated pregnancy to a limited extent.
INTERPRETATION & CONCLUSIONS: Inter-individual variations in CL and in CL changes were large. Thus, it was not practical to predict spontaneous onset of labour by sonographic CL measurement near term. Post-dated pregnancy may be predicted with limited success. Further studies should explore other parameters, in addition to CL.
关于足月妊娠时连续测量宫颈长度(CL)以预测自发性分娩开始的数据稀缺且相互矛盾。本研究旨在通过经阴道超声(TVS)和经腹部超声(TAS)观察足月时初产妇 CL 的变化,以预测自发性分娩的开始。
仅纳入经阴道超声检查证实为头位单胎妊娠且孕周准确的初产妇。从 36 孕周开始,每周由一名超声医生进行一次超声 CL 测量。在仰卧位下,使用合适的探头进行经腹部和经阴道测量。
共评估了 104 例自发性分娩的产妇。从 36 周到 40 周,TVS 和 TAS 的 CL 测量值均存在很大差异,尽管两种测量方法密切相关。在分娩前的最后三周,CL 均值发生了显著变化。然而,只有三分之一的产妇在最后三周 CL 变化超过 5mm/周。TVS 和 TAS 测量的最后 CL 值与分娩时的孕周之间相关性较差。在 38 孕周时,TVS 测量的长度>3.1mm 可在一定程度上预测过期妊娠。
个体间 CL 和 CL 变化的差异较大。因此,在接近足月时通过超声 CL 测量预测自发性分娩开始并不实用。对于过期妊娠,预测可能有一定的效果。应进一步研究除 CL 以外的其他参数。