在合成培养基中生产贝利那明和新的代谢产物。
Production of bellenamine and new metabolites in a synthetic medium.
作者信息
Ikeda Y, Gomi S, Hamada M, Kondo S, Takeuchi T
机构信息
Institute of Microbial Chemistry, Tokyo, Japan.
出版信息
J Antibiot (Tokyo). 1992 Nov;45(11):1763-6. doi: 10.7164/antibiotics.45.1763.
PMID:1468984
Abstract
A streptomyces antibiotic, bellenamine has been produced in a simple synthetic medium consisting of D-galactose, dextrin, ammonium sulfate and calcium carbonate. Three new minor metabolites, N-(aminomethyl)succinamic acid, 1'-N-acetylbellenamine and D-beta-lysinamide have been isolated from the synthetic medium culture. They showed no antibiotic activity.
摘要
一种链霉菌抗生素——贝利那明，是在一种由D-半乳糖、糊精、硫酸铵和碳酸钙组成的简单合成培养基中产生的。从该合成培养基培养物中分离出了三种新的次要代谢产物，即N-(氨甲基)琥珀酰胺酸、1'-N-乙酰贝利那明和D-β-赖氨酸酰胺。它们没有显示出抗生素活性。
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