Kanmaz Turan, Demirbilek Savas, Ozardali Ilyas, Safali Mukerrem, Guran Sefik, Yucesan Selcuk
Department of Pediatric Surgery, Harran University, Faculty of Medicine, Sanliurfa, Turkey.
Pediatr Pathol Mol Med. 2003 Sep-Oct;22(5):405-10. doi: 10.1080/pdp.22.5.405.410.
Pediatric nonfunctioning adrenocortical carcinoma is a very rare tumor. A 4-year-old girl was admitted complaining of abdominal pain. Physical examination revealed an abdominal mass. There were no clinical or laboratory signs of hormonal abnormality. Abdominal ultrasonography revealed a polylobular mass. Intravenous pyelography showed marked compression of the kidney by a tumor. The tumor was excised together with the right kidney. The histopathological diagnosis was adrenocortical carcinoma. Although there is a greater incidence of germ line p53 mutations with adrenocortical carcinoma, the tumor suppressor gene p53 was not mutated in our case. The girl died 2 months after surgery from complications of chemotherapy.
