Ando K, Tokura H, Matsuoka H, Taylor D, Chinzei Y
Department of Medical Zoology, Mie University School of Medicine, Tsu, Japan.
J Helminthol. 1992 Mar;66(1):53-61. doi: 10.1017/s0022149x00012566.
The life cycle of Gnathostoma nipponicum was examined by field survey and by experimental infection of animals with the larvae. Naturally infected larval G. nipponicum were found in loaches, catfish, and snakes. Experimentally, loaches, killifishes, frogs, salamanders, mice, and rats were successfully infected with the early third-stage larvae of G. nipponicum obtained from copepods (the first intermediate host), whereas snakes, quails, and weasels were not. Frogs, snakes, quails, and rats were experimentally infected with the advanced third-stage larvae (AdL3) from loaches. These results reveal that some species of fishes, amphibians and mammals can act as the second intermediate host and that some species of reptiles, birds and mammals can act as a paratenic host. The life cycle was completed in weasels, the definitive host, which were infected with AdL3 from loaches and started to evacuate eggs of G. nipponicun in faeces on days 65-90 postinfection.
通过野外调查以及用幼虫对动物进行实验性感染，对日本颚口线虫的生命周期进行了研究。在泥鳅、鲶鱼和蛇体内发现了自然感染的日本颚口线虫幼虫。实验中，从桡足类动物（第一中间宿主）获得的日本颚口线虫早期第三期幼虫成功感染了泥鳅、鳉鱼、青蛙、蝾螈、小鼠和大鼠，而蛇、鹌鹑和黄鼠狼未被感染。青蛙、蛇、鹌鹑和大鼠被实验性感染了来自泥鳅的晚期第三期幼虫（AdL3）。这些结果表明，某些鱼类、两栖动物和哺乳动物物种可作为第二中间宿主，某些爬行动物、鸟类和哺乳动物物种可作为转续宿主。在作为终末宿主的黄鼠狼体内完成了生命周期，这些黄鼠狼被来自泥鳅的AdL3感染，并在感染后第65 - 90天开始通过粪便排出日本颚口线虫卵。
