[三硝基甲苯（TNT）接触工人晶状体混浊度与尿中2,6-二硝基-4-氨基甲苯（DNAT）水平关系的研究]
[Study on the relationship between the opacity of lens and the levels of 2, 6-dinitro-4-amino-toluene (DNAT) in the urine of workers exposed to trinitrotoluene(TNT)].
作者信息
Zhu Zhongde, Li Zhilan, Mi Fatai, Lian Suqin, Dong Pengcheng, Wu Yuhua, Sun Xiaohua
机构信息
First Affiliated Hospital, Lanzhou Medical College, Lanzhou 730000, China.
出版信息
Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi. 2002 Feb;20(1):42-3.
OBJECTIVE
To find out the relationship between the opacity in lens and the contents of 2,6-dinitro-4-amino-toluene(DNAT) in the urine of exposed workers.
METHODS
Testing the exposed worker's lens and measuring the contents of DNAT in the urine after work.
RESULTS
When the opacity of the lens occurred, the contents of DNAT in the urine(2.38 mg/L) of workers exposed to TNT were significantly higher than those without opacity in lens(1.44 mg/L) (P < 0.05).
CONCLUSION
The severity of opacity of lens increased with the contents of DNAT raised in the urine. The threshold value suggested by ILO is not applicable to Chinese occupational population, which recommends the contents of DNAT(30 mg/L) in the urine for the workers exposed to TNT as biological occupational exposed limits.
目的
探讨接触工人晶状体混浊情况与尿中2,6-二硝基-4-氨基甲苯（DNAT）含量之间的关系。
方法
对接触工人的晶状体进行检测，并于下班后测定尿中DNAT含量。
结果
晶状体出现混浊时，接触三硝基甲苯（TNT）工人尿中DNAT含量（2.38mg/L）显著高于晶状体未出现混浊者（1.44mg/L）（P<0.05）。
结论
晶状体混浊程度随尿中DNAT含量升高而加重。国际劳工组织（ILO）建议的阈值不适用于中国职业人群，其推荐将接触TNT工人尿中DNAT含量（30mg/L）作为生物职业接触限值。
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