Ross Ian L, Willmore Rina, Heuzenroeder Michael W
Infectious Diseases Laboratories, Institute of Medical and Veterinary Science, Adelaide, South Australia, 5000, Australia.
Int J Med Microbiol. 2003 Nov;293(5):371-5. doi: 10.1078/1438-4221-00272.
Fluorescent amplified fragment length polymorphism (FAFLP) analysis was performed on 68 isolates of Salmonella enterica subsp. salamae serovar Sofia (S. Sofia). Fifty eight isolates were obtained over a period of approximately 15 years from a range of human, chicken industry and environmental sources throughout Australia. A further ten isolates were identified from human and poultry sources in Israel from 1972 to 1987. Analysis of FAFLP profiles for fragments between 50 to 500 base pairs in length indicated distinct clusters of isolates. All but seven isolates clustered into four groups of >90% similarity and all isolates displayed at least 70% similarity with each other. No cluster could be attributed to a particular geographical, temporal or source-of-isolation origin. It is concluded that S. Sofia is genetically variable with certain clones persisting over time but no group appears unique to Australia.
对68株肠炎沙门氏菌萨拉马亚种索非亚血清型（S. Sofia）进行了荧光扩增片段长度多态性（FAFLP）分析。在大约15年的时间里，从澳大利亚各地的一系列人类、养鸡业和环境来源中获得了58株菌株。另外10株菌株是1972年至1987年期间从以色列的人类和家禽来源中鉴定出来的。对长度在50至500个碱基对之间的片段进行FAFLP图谱分析，结果表明菌株存在明显的聚类。除7株菌株外，所有菌株聚为四组，相似度>90%，所有菌株之间的相似度至少为70%。没有一个聚类可归因于特定的地理、时间或分离源。结论是，S. Sofia具有遗传变异性，某些克隆随时间持续存在，但没有一个组是澳大利亚独有的。
