Day Terry A, Deveikis John, Gillespie M Boyd, Joe John K, Ogretmen Besim, Osguthorpe J David, Reed Susan G, Richardson Mary S, Rossi Michael, Saini Ranjiv, Sharma Anand K, Stuart Robert K
Head and Neck Tumor Program, Hollings Cancer Center, Medical University of South Carolina, 96 Jonathan Lucas Street, Charleston, SC 29425, USA.
Curr Treat Options Oncol. 2004 Feb;5(1):11-26. doi: 10.1007/s11864-004-0002-x.
Treatment and cure of salivary gland neoplasms requires surgical intervention in most cases. For parotid neoplasms, the most common surgical procedure performed is the superficial parotidectomy with facial nerve preservation. Postoperative radiation therapy is indicated in high-grade salivary gland malignancies and malignancies with increased risk of locoregional recurrence. Primary radiation, including neutron beam techniques, may play a role in certain histologic types or nonoperative candidates. Chemotherapy has yet to result in improvements in survival or quality of life in the treatment of salivary gland malignancy. Advances in radiation therapy techniques, including intensity-modulated radiation therapy, provide opportunities for reduced morbidity.
在大多数情况下，涎腺肿瘤的治疗和治愈需要手术干预。对于腮腺肿瘤，最常施行的外科手术是保留面神经的腮腺浅叶切除术。术后放射治疗适用于高级别涎腺恶性肿瘤以及局部区域复发风险增加的恶性肿瘤。包括中子束技术在内的原发性放射治疗可能在某些组织学类型或不适合手术的患者中发挥作用。在涎腺恶性肿瘤的治疗中，化疗尚未使生存率或生活质量得到改善。放射治疗技术的进步，包括调强放射治疗，为降低发病率提供了机会。
