Ishikawa Y, Arioka H, Kobayashi R, Naito H
Department of Pediatrics, Hokkaido University School of Medicine.
Rinsho Ketsueki. 1992 Nov;33(11):1697-702.
Two children with severe and moderate aplastic anemia received combination treatment with methylprednisolone, antilymphocyte globulin and cyclosporine. One child (severe type) was given 2 courses of high dose methylprednisolone during the last 4 weeks without improvement prior to this combination therapy. The other child (moderate type) was not previously treated. Both patients showed complete response within 3 months following this therapy. Serious side effects were not observed. Combination therapy of these three drugs may be beneficial for patients with aplastic anemia.
两名患有重度和中度再生障碍性贫血的儿童接受了甲泼尼龙、抗淋巴细胞球蛋白和环孢素的联合治疗。一名儿童（重度类型）在接受这种联合治疗前的最后4周内接受了2个疗程的高剂量甲泼尼龙治疗，但病情没有改善。另一名儿童（中度类型）之前未接受过治疗。两名患者在接受该治疗后的3个月内均显示完全缓解。未观察到严重的副作用。这三种药物的联合治疗可能对再生障碍性贫血患者有益。
