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我们应该对肝移植术后患者的肾脏进行活检吗?

Should we biopsy kidneys of patients post-liver transplant?

作者信息

Chonchol M, Wachs M, Taylor J, Popovtzer M M

机构信息

Department of Medicine, Division of Renal Diseases and Hypertension, University of Colorado Health Sciences Center, 4200 E. 9th Avenue, Box C-281, Denver, CO 80262, USA.

出版信息

Transplant Proc. 2003 Dec;35(8):3035-8. doi: 10.1016/j.transproceed.2003.10.079.

DOI:10.1016/j.transproceed.2003.10.079
PMID:14697972
Abstract

Thirty days after orthotropic liver transplantation, a 52-year-old Hispanic male developed full-blown nephrotic syndrome. Although the patient was posttransplantation, he underwent a kidney biopsy under real-time ultrasound guidance. The pathological specimen revealed membranous nephropathy. A change in the immunosuppressive regimen resulted in a rapid decrease in urinary protein excretion, leading to resolution of the nephrotic syndrome. We report this case to illustrate the precautions that need to be taken when liver transplant patients require a kidney biopsy.

摘要

在原位肝移植术后30天,一名52岁的西班牙裔男性出现了典型的肾病综合征。尽管患者处于移植后状态,但仍在实时超声引导下进行了肾活检。病理标本显示为膜性肾病。免疫抑制方案的改变导致尿蛋白排泄迅速减少,肾病综合征得以缓解。我们报告此病例以说明肝移植患者需要进行肾活检时应采取的预防措施。

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