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[乙酰胆碱对黄鼠(Citellus erythrogenus)脑突触体三磷酸腺苷酶活性的作用]

[Action of acetylcholine on the adenosine triphosphatase activity of the brain synaptosomes of the suslik, Citellus erythrogenus].

作者信息

Vysochina T K

出版信息

Zh Evol Biokhim Fiziol. 1978 Jan-Feb;14(1):88-90.

PMID:146989
Abstract

In experiments in vitro at 37 and 17 degrees C, studies have been made of the effect of ACh upon the activity of Mg- and Na,K-ATPase of brain synaptosomes of the ground squirrel in summer animals and during winter hibernation. ACh (6 mM) decreases the activity of ATPases by 23-33% at 37 degrees C. During winter hibernation, the inhibitory effect of ACh is increased resulting in lower values of residual ATPase activity after the effect of ACh as compared with those obtained in summer period.

摘要

在37摄氏度和17摄氏度的体外实验中,研究了乙酰胆碱对夏季和冬季冬眠期间地松鼠脑突触体中镁离子和钠钾离子ATP酶活性的影响。在37摄氏度时,6毫摩尔的乙酰胆碱使ATP酶活性降低23%至33%。在冬季冬眠期间,乙酰胆碱的抑制作用增强,与夏季相比,乙酰胆碱作用后ATP酶的残余活性值更低。

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