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医源性椎管内表皮样囊肿:两例报告并文献复习

Iatrogenic intraspinal epidermoid tumor: two cases and a review of the literature.

作者信息

Ziv Eli T, Gordon McComb J, Krieger Mark D, Skaggs David L

机构信息

Department of Orthopaedic Surgery, Children's Hospital Los Angeles, University of Southern California School of Medicine, Los Angeles, CA 90027, USA.

出版信息

Spine (Phila Pa 1976). 2004 Jan 1;29(1):E15-8. doi: 10.1097/01.BRS.0000104118.07839.44.

Abstract

STUDY DESIGN

Two cases of patients whom intraspinal epidermoid tumors presented and were successfully removed 6 years after neonatal lumbar puncture are reported.

OBJECTIVE

To describe the presentation of this type of spinal tumor and strategies for diagnosis and treatment.

SUMMARY OF BACKGROUND DATA

Cells iatrogenically implanted into the spinal canal during lumbar puncture can slowly grow until symptomatic. Diagnosis can be difficult and is often delayed. MRI appears to offer some advantages in diagnosis provided that gadolinium is used. Treatment is by surgical excision.

METHODS

The first patient, a 6-year-old boy, presented with severe episodic hip pain of unknown etiology. MRI of the lumbar spine revealed a 1-cm epidermoid at L1-L2. The second child, a 6-year-old girl, presented with low back pain and dragging of the feet. MRI revealed a mass at L3.

RESULTS

In both cases, complete excision via lumbar laminectomy was performed. Both patients were asymptomatic at the 1-year follow-up with resolution of preoperative weakness.

CONCLUSIONS

This study highlights an uncommon but not rare tumor that may present to the spine specialist in a variety of ways. The diagnosis is often delayed. The advent of MRI has improved the ease and accuracy of diagnosis. Complete excision is usually possible and is curative.

摘要

研究设计

报告2例新生儿腰椎穿刺6年后出现椎管内表皮样囊肿并成功切除的病例。

目的

描述此类脊柱肿瘤的表现以及诊断和治疗策略。

背景资料总结

腰椎穿刺时医源性植入椎管内的细胞可缓慢生长直至出现症状。诊断可能困难且常被延误。如果使用钆,磁共振成像(MRI)在诊断方面似乎具有一些优势。治疗方法是手术切除。

方法

首例患者为一名6岁男孩,出现病因不明的严重发作性髋部疼痛。腰椎MRI显示L1-L2水平有一个1厘米的表皮样囊肿。第二个孩子是一名6岁女孩,出现腰痛和足部拖地症状。MRI显示L3水平有一个肿块。

结果

两例均通过腰椎椎板切除术进行了完整切除。两名患者在1年随访时均无症状,术前的虚弱症状也已缓解。

结论

本研究强调了一种虽不常见但也不罕见的肿瘤,它可能以多种方式出现在脊柱专科医生面前。诊断常常被延误。MRI的出现提高了诊断的便利性和准确性。通常可以进行完整切除且具有治愈性。

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