Stricker B H, de Jong P A, Schreuder F, Bijlmer-Iest J C, Herrmann W A, van Ulsen J
Bureau Bijwerkingen Geneesmiddelen, Rijswijk.
Ned Tijdschr Geneeskd. 1992 Dec 5;136(49):2438-40.
Terbinafine is a new antifungal agent for oral treatment of dermatomycosis. Seven patients are reported who developed taste loss after treatment with terbinafine. In four of them, taste loss was complete while one patient was still able to taste sweet products, and a second and third patient no longer tasted salty and sweet products, respectively. In all patients, the onset of the adverse reaction occurred 4-8 weeks after starting treatment. As far as known, taste loss is a transient effect which disappears within 3-6 weeks after discontinuation of terbinafine.
特比萘芬是一种用于口服治疗皮肤真菌病的新型抗真菌药。本文报道了7例患者在使用特比萘芬治疗后出现味觉丧失的情况。其中4例味觉完全丧失，1例仍能尝出甜味产品，另外2例分别不能尝出咸味和甜味产品。所有患者的不良反应均在开始治疗后4 - 8周出现。据了解，味觉丧失是一种短暂效应，在停用特比萘芬后3 - 6周内会消失。
