Ozaslan Cihangir, Kuru Bekir
Department of Surgery, Ankara Education and Research Hospital, Ankara, Turkey.
Am J Surg. 2004 Jan;187(1):69-72. doi: 10.1016/j.amjsurg.2002.12.003.
Lymphedema is one of the major long-term complications of axillary dissection. This study was designed to investigate the risk factors that are predicted to effect the development of lymphedema after complete axillary dissection.
Two hundred forty patients who had undergone modified radical mastectomy with complete axillary dissection were examined at least 18 months after the surgery. The effects of age, diabetes, smoking, hypertension, chemotherapy, radiotherapy, tamoxifen use, stage, body mass index, number of the removed and metastatic lymph nodes, and total volume of the wound drainage on the development of lymphedema were analyzed.
Lymphedema developed in 68 (28%) of the 240 cases. Axillary radiotherapy and body mass index were found to increase the incidence of the lymphedema.
Women who had the combination of full axillary dissection and axillary radiotherapy carry a significant risk of lymphedema.
淋巴水肿是腋窝清扫术的主要长期并发症之一。本研究旨在调查预计会影响完全腋窝清扫术后淋巴水肿发生的危险因素。
对240例行改良根治性乳房切除术并完全腋窝清扫术的患者在术后至少18个月进行检查。分析年龄、糖尿病、吸烟、高血压、化疗、放疗、他莫昔芬使用、分期、体重指数、切除及转移淋巴结数量以及伤口引流总量对淋巴水肿发生的影响。
240例患者中有68例（28%）发生淋巴水肿。发现腋窝放疗和体重指数会增加淋巴水肿的发生率。
接受完全腋窝清扫术和腋窝放疗联合治疗的女性发生淋巴水肿的风险显著。
