Weissman Myrna M, Feder Adriana, Pilowsky Daniel J, Olfson Mark, Fuentes Milton, Blanco Carlos, Lantigua Rafael, Gameroff Marc J, Shea Steven
Division of Clinical and Genetic Epidemiology, New York State Psychiatric Institute, New York, NY, USA.
J Affect Disord. 2004 Feb;78(2):93-100. doi: 10.1016/s0165-0327(02)00301-4.
Studies of depressed mothers have generally been conducted in psychiatric settings with non-minority, middle-class women. Primary care has an increasing role in early detection and treatment, especially for the poor who have less access to specialized mental health services. Data on the relationship between maternal depression and problems in the offspring in a primary care context could help physicians to more effectively identify children in need of psychiatric help.
All mothers aged 25 to 55 from a systematic sample of consecutive adults (response rate, 80%) in an urban general medicine practice were screened using the PRIME-MD Patient Health Questionnaire (PHQ). Mothers who screened positive for major depression (n=85); other psychiatric disorders, but not major depression (n=67); or no psychiatric disorders (n=191) were compared on their children's history of emotional problems, unmet need for mental health treatment, parent-child discord, maternal functional status and mental health treatment.
Compared to non-psychiatric controls, depressed mothers reported a three-times greater risk of serious emotional problems in their children (95% confidence interval [CI], 1.7-6.1); a four-times greater risk of having their children's problems left untreated (95% CI, 2.3-8.2), and a 10-times greater risk of having poor mother-child relations within the past month (95% CI, 3.9-29.4). Depressed mothers reported more functional disability, more psychiatric treatment and more problems in their offspring than mothers with non-depressive psychiatric disorders. Although a majority of mothers (regardless of psychiatric status) believed that counseling (96%) or medication (84%) should be offered to those with serious emotional problems, only about half (49%) of the depressed mothers had received mental health treatment in the past month.
Children were not assessed directly.
The children of low-income depressed women at a general medicine practice were reported to have a greatly increased risk for emotional problems. Many mothers had not received treatment for their own emotional problems. By enquiring about the emotional health of children of adult primary care patients, primary care providers have an opportunity to promote early detection and to facilitate appropriate treatment for both the mothers and their children.
对抑郁母亲的研究通常是在精神科环境中针对非少数族裔的中产阶级女性进行的。初级保健在早期发现和治疗中发挥着越来越重要的作用,尤其是对于那些难以获得专业心理健康服务的贫困人口。在初级保健环境中,有关母亲抑郁与后代问题之间关系的数据有助于医生更有效地识别需要精神科帮助的儿童。
对城市综合内科诊所中连续就诊的成年人进行系统抽样,选取所有年龄在25至55岁之间的母亲(应答率为80%),使用PRIME-MD患者健康问卷(PHQ)进行筛查。对筛查出重度抑郁阳性的母亲(n = 85)、患有其他精神疾病但非重度抑郁的母亲(n = 67)以及无精神疾病的母亲(n = 191),比较她们孩子的情绪问题史、未满足的心理健康治疗需求、亲子关系不和谐情况、母亲的功能状态以及心理健康治疗情况。
与非精神疾病对照组相比,抑郁母亲报告其孩子出现严重情绪问题的风险高3倍(95%置信区间[CI],1.7 - 6.1);孩子问题未得到治疗的风险高4倍(95% CI,2.3 - 8.2),且在过去一个月内亲子关系差的风险高10倍(95% CI,3.9 - 29.4)。与患有非抑郁性精神疾病的母亲相比,抑郁母亲报告其功能残疾更多、接受的精神科治疗更多,且其后代存在的问题更多。尽管大多数母亲(无论精神状态如何)认为对于有严重情绪问题的人应提供咨询(96%)或药物治疗(84%),但在过去一个月中,只有约一半(49%)的抑郁母亲接受过心理健康治疗。
未直接评估儿童。
据报告,在综合内科诊所中,低收入抑郁女性的孩子出现情绪问题的风险大幅增加。许多母亲自身的情绪问题未得到治疗。通过询问成年初级保健患者孩子的情绪健康状况,初级保健提供者有机会促进早期发现,并为母亲及其孩子推动适当的治疗。