Milkereit G, Morr M, Thiem J, Vill V
Institut für Organische Chemie, Universität Hamburg, Martin-Luther-King-Platz 6, 20146, Hamburg, Germany.
Chem Phys Lipids. 2004 Jan;127(1):47-63. doi: 10.1016/j.chemphyslip.2003.09.007.
As part of a series of papers, the influence of carbohydrate headgroups and aliphatic chains on the mesogenic properties of glycolipids was investigated. Alkyl glycosides with different types of aliphatic chains were synthesised. Neutral glycolipids were oxidized to their uronic acid derivatives, using the well established TEMPO-oxidation. For comparison a 6-deoxy-6-amino alkylglucopyranoside was synthesised. In addition, the thermotropic and lyotropic phase behaviour of the synthesised compounds were investigated. The thermotropism was characterised by polarising microscopy, the lyotropism by the contact preparation method.
作为系列论文的一部分，研究了碳水化合物头部基团和脂肪链对糖脂介晶性质的影响。合成了具有不同类型脂肪链的烷基糖苷。使用成熟的TEMPO氧化法将中性糖脂氧化为其糖醛酸衍生物。为作比较，合成了一种6-脱氧-6-氨基烷基吡喃葡萄糖苷。此外，还研究了合成化合物的热致和溶致相行为。热致性通过偏光显微镜表征，溶致性通过接触制备法表征。
