Healy E, Kelly P, Mulcahy F M, Clancy L
Peamount Hospital, Newcastle, Co. Dublin, Ireland.
Respir Med. 1992 Nov;86(6):491-4. doi: 10.1016/s0954-6111(96)80008-4.
In the period 1980-1985, we treated 1641 patients for tuberculosis of whom two were known to be intravenous drug users (IVDU) and none had HIV infection. Of the next 1000 patients treated for tuberculosis (January 1986-December 1989), six were HIV-negative intravenous drug users (IVDU), 18 patients were HIV-positive (12 IVDU; six homosexual/bisexual). Statistical analysis (chi 2) showed a numerically small but statistically significant (P < 0.00001, d.f. = 1, chi 2 = 20.38) increase in intravenous drug users with a diagnosis of tuberculosis. The HIV-positive patients who completed treatment responded well to anti-tuberculous drugs. The importance of tuberculosis in the context of HIV infection is that it is preventable, treatable and is the only bacterial infection to which HIV subjects are prone which can be readily transmitted to a non-HIV infected subject.
在1980年至1985年期间，我们治疗了1641例结核病患者，其中已知有2例为静脉注射吸毒者（IVDU），且均无HIV感染。在接下来治疗的1000例结核病患者中（1986年1月至1989年12月），有6例为HIV阴性的静脉注射吸毒者（IVDU），18例为HIV阳性（12例IVDU；6例同性恋/双性恋者）。统计分析（卡方检验）显示，诊断为结核病的静脉注射吸毒者人数虽在数值上增加不多，但具有统计学显著性（P < 0.00001，自由度 = 1，卡方值 = 20.38）。完成治疗的HIV阳性患者对抗结核药物反应良好。结核病在HIV感染背景下的重要性在于，它是可预防、可治疗的，并且是HIV感染者易患的唯一一种可轻易传播给未感染HIV者的细菌感染。
