与烯烃相连的肟醚的锡烷基自由基加成环化反应。

Stannyl radical addition-cyclization of oxime ethers connected with olefins.

作者信息

Miyabe Hideto, Tanaka Hirotaka, Naito Takeaki

机构信息

Kobe Pharmaceutical University, Motoyamakita, Higashinada-ku, Kobe 658-8558, Japan.

出版信息

Chem Pharm Bull (Tokyo). 2004 Jan;52(1):74-8. doi: 10.1248/cpb.52.74.

DOI:10.1248/cpb.52.74

PMID:14709871

Abstract

Stannyl radical addition-cyclization of oxime ethers connected with olefin moieties was studied. The radical reactions proceeded effectively by the use of triethylborane as a radical initiator to provide the functionalized pyrrolidines via a carbon-carbon bond-forming process.

摘要

研究了与烯烃部分相连的肟醚的锡烷基自由基加成环化反应。通过使用三乙基硼烷作为自由基引发剂，自由基反应有效地进行，通过碳-碳键形成过程提供功能化的吡咯烷。