Attarian S, Serratrice J, Mazodier C, Disdier P, Azulay J-P, Pouget J
Service de Neurologie et des Maladies Neuromusculaires, CHU La Timone, Marseille.
Rev Neurol (Paris). 2003 Nov;159(11):1046-8.
Visceral leishmaniasis is an endemic parasitic infection rarely observed in association with Guillain-Barré syndrome in immunocompetent patients. A 40-year-old immunocompetent woman was admitted to our unit with recent onset difficulty in walking. The neurological examination and electrophysiological study led to the diagnosis of Guillain-Barré syndrome. During hospitalization, she developed cytopenia involving all three lines revealing visceral leishmaniasis. A few cases of visceral leishmaniasis with neuropathy have been reported, mainly in tropical regions. Neuropathological manifestations of visceral leishmaniasis are probably underestimated. The question is whether Guillain-Barré syndrome and visceral leishmaniasis are causally related.
内脏利什曼病是一种地方性寄生虫感染，在免疫功能正常的患者中很少与吉兰-巴雷综合征相关联。一名40岁免疫功能正常的女性因近期出现行走困难入住我们科室。神经系统检查和电生理研究诊断为吉兰-巴雷综合征。住院期间，她出现了全血细胞减少，提示内脏利什曼病。已有少数内脏利什曼病合并神经病变的病例报道，主要在热带地区。内脏利什曼病的神经病理学表现可能被低估了。问题是吉兰-巴雷综合征与内脏利什曼病是否存在因果关系。
