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宫颈环扎位置会影响围产期结局吗?

Does cerclage location influence perinatal outcome?

作者信息

Rust Orion A, Atlas Robert O, Meyn Joseph, Wells Mark, Kimmel Sharon

机构信息

Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Lehigh Valley Hospital and Health Network, CC & I-78, PO Box 689, Allentown, PA 18105-1556, USA.

出版信息

Am J Obstet Gynecol. 2003 Dec;189(6):1688-91. doi: 10.1016/s0002-9378(03)00779-8.

Abstract

OBJECTIVE

The study was undertaken to measure cerclage location within the cervix and to determine whether placement closer to the internal os is related to perinatal outcome.

STUDY DESIGN

We analyzed data collected during a randomized trial of cervical cerclage versus no cerclage that was conducted at Lehigh Valley Hospital between May 1998 and June 2001 in women with ultrasound findings of short cervix less than 25 mm or funneling between 16 and 24 weeks' gestation. Women who were randomly assigned to the cerclage arm had cervical measurements performed before cerclage, including dilation of the internal os, depth of membrane prolapse into the endocervical canal, cervical length below any funnel (distal length), and total cervical length (including any funnel). Measurements obtained after cerclage placement included the distance from external os to cerclage (A), and a repeat of the same four measurements. The distance from the external os to the cerclage (A) was divided by the total cervical length (B) and a cerclage to cervical length ratio (A/B) was calculated. The relationship between these measurements and gestational age at birth was assessed by linear regression analysis.

RESULTS

Of 150 patients enrolled, 74 received a McDonald cerclage suture. Mean distal cervical length was 1.9+/-0.9 cm before and 2.9+/-1.0 cm after cerclage (P=.001). The mean distance between the cerclage and external os (A) was 1.8+/-0.6 cm; the total cervical length after cerclage (B) was 3.6+/-0.9 cm. The mean cerclage to cervical length ratio (A/B) was 0.5+/-0.1. Linear regression analysis did not demonstrate a correlation between either the cerclage to external os measurement (A) or the cervical length ratio (A/B) and gestational age at birth (R(2)=0.0006 and 0.008, P=.8 and.6, respectively).

CONCLUSION

The length of the cervix below the level of cerclage is not related to duration of pregnancy in women treated with cerclage because of ultrasound evidence of cervical effacement.

摘要

目的

本研究旨在测量宫颈内宫颈环扎的位置,并确定其位置更靠近宫颈内口是否与围产期结局相关。

研究设计

我们分析了1998年5月至2001年6月在利哈伊谷医院进行的一项宫颈环扎术与不进行环扎术的随机试验中收集的数据,该试验针对超声检查发现宫颈短(小于25mm)或在妊娠16至24周之间宫颈管漏斗形成的女性。随机分配到环扎组的女性在进行环扎术前进行宫颈测量,包括宫颈内口扩张程度、胎膜脱垂至宫颈管内的深度、任何漏斗下方的宫颈长度(远端长度)以及宫颈总长度(包括任何漏斗)。环扎术后获得的测量值包括从宫颈外口到环扎处的距离(A),以及重复相同的四项测量值。将从宫颈外口到环扎处的距离(A)除以宫颈总长度(B),计算出环扎与宫颈长度比值(A/B)。通过线性回归分析评估这些测量值与出生孕周之间的关系。

结果

在纳入的150例患者中,74例接受了麦克唐纳宫颈环扎缝合术。环扎术前宫颈远端平均长度为1.9±0.9cm,环扎术后为2.9±1.0cm(P = 0.001)。环扎处与宫颈外口之间的平均距离(A)为1.8±0.6cm;环扎术后宫颈总长度(B)为3.6±0.9cm。环扎与宫颈长度的平均比值(A/B)为0.5±0.1。线性回归分析未显示环扎处与宫颈外口测量值(A)或宫颈长度比值(A/B)与出生孕周之间存在相关性(R²分别为0.0006和0.008,P值分别为0.8和0.6)。

结论

对于因超声显示宫颈消退而接受环扎术治疗的女性,环扎水平以下的宫颈长度与妊娠持续时间无关。

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