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[强化甲状腺评估在男性不育症中的价值]

[Value of intensive thyroid assessment in male infertility].

作者信息

Trummer H, Ramschak-Schwarzer S, Haas J, Pummer K, Leb G

机构信息

Universitätsklinik für Urologie, Auenbruggerplatz 7, A-8036 Graz.

出版信息

Acta Med Austriaca. 2003;30(4):103-4.

Abstract

In infertile men thyroid hormone and antibody testing was performed and correlated with the results of semen analyses. Evaluation included semen analyses, physical examination, evaluation of sex steroid hormones, thyroid hormones (bTSH, fT4, fT3) and thyroid antibody testing (TGA, TPO-Ab, TRAK). Furthermore 45 men with normal thyroid function were scheduled for TRH testing. No one was diagnosed as having manifest hypo- or hyperthyroidism. Latent thyroid dysfunction had no effect on semen parameters. Elevated TPO-Ab were significantly correlated with reduction in motility of spermatozoa. The routine assessment of thyroid hormones and antibodies in infertile men is not recommended. Subclinical hypothyroidism as a result of TRH testing is a rare finding in infertile men.

摘要

对不育男性进行了甲状腺激素和抗体检测,并将其与精液分析结果进行关联。评估内容包括精液分析、体格检查、性类固醇激素评估、甲状腺激素(促甲状腺激素、游离甲状腺素、游离三碘甲状腺原氨酸)和甲状腺抗体检测(甲状腺球蛋白抗体、甲状腺过氧化物酶抗体、促甲状腺素受体抗体)。此外,安排了45名甲状腺功能正常的男性进行促甲状腺激素释放激素检测。没有人被诊断为明显的甲状腺功能减退或亢进。潜在的甲状腺功能障碍对精液参数没有影响。甲状腺过氧化物酶抗体升高与精子活力降低显著相关。不建议对不育男性常规评估甲状腺激素和抗体。促甲状腺激素释放激素检测导致的亚临床甲状腺功能减退在不育男性中是罕见的发现。

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