Brinch L J, Jacobsen M B
Hematologisk seksjon, Rikshospitalet, Oslo.
Tidsskr Nor Laegeforen. 1992 Nov 30;112(29):3670-1.
We describe a patient with moderate von Willebrand's disease who developed severe hyponatremia during prophylaxis with 1-deamino-8D-arginine vasopressin (desmopressin) to prevent bleeding in connection with surgery. This is a rare complication to desmopressin treatment in adults. Our present policy is to restrict administration of desmopressin to three 12-hourly infusions, to measure serum sodium before and during the treatment period, to determine body weight daily and to restrict administration of fluids.
我们描述了一名中度血管性血友病患者，在使用去氨加压素预防手术相关出血期间发生了严重低钠血症。这是成人去氨加压素治疗中一种罕见的并发症。我们目前的策略是将去氨加压素的给药限制为每12小时输注三次，在治疗期间前后测量血清钠，每天测定体重，并限制液体摄入。
