Jensen A B
Onkologisk afdeling R, Odense Sygehus.
Ugeskr Laeger. 1992 Dec 14;154(51):3666-70.
Cancer of the breast is the commonest from of cancer of women in Denmark and the incidence is increasing. At present, a series of risk and prognostic factors are recognised. These are primarily related to the endocrine system. Other factors, including the significance of psychological and social factors, have been investigated. A review of the literature concerning the significance of psychological and social factors as risk and prognostic factors, respectively, reveals that the methodological problems in these investigations are considerable and multifarious. On the basis of a review of the literature, it is concluded, that there is no proof that psychosocial factors influence the disease of cancer of the breast. Nevertheless, certain evidence exits in the literature suggesting a connection between inhibition of aggression and an introverted personality and the development of cancer of the breast while, in some investigations, ability to cope has a certain significance as a prognostic factor. Investigations of psychosocial intervention as the actual antineoplastic treatment are very few and the results are difficult to interpret. It may be concluded that no basis exists to justify employment of psychosocial intervention as an actual form of treatment with the object of improving survival.
在丹麦,乳腺癌是女性中最常见的癌症类型,且发病率正在上升。目前,一系列风险和预后因素已得到确认。这些因素主要与内分泌系统有关。其他因素,包括心理和社会因素的重要性,也已得到研究。对有关心理和社会因素分别作为风险因素和预后因素的重要性的文献进行综述后发现,这些研究中的方法学问题相当多且繁杂。基于对文献的综述,得出的结论是,没有证据表明心理社会因素会影响乳腺癌疾病。然而,文献中存在某些证据表明,抑制攻击性和内向型人格与乳腺癌的发展之间存在联系,而在一些研究中,应对能力作为预后因素具有一定意义。将心理社会干预作为实际的抗肿瘤治疗方法的研究非常少,且结果难以解释。可以得出结论,没有依据证明将心理社会干预作为一种实际治疗形式来提高生存率是合理的。