Onrat Ersel, Kaya Dayimi, Onrat Serap Tutgun
Department of Cardiology, School of Medicine, Faculty of Science, Afyon Kocatepe University, Turkey.
Acta Cardiol. 2003 Dec;58(6):567-70. doi: 10.2143/AC.58.6.2005324.
We present a case of a young boy in whom lacrimo-auriculo-dental-digital (LADD) syndrome with QT prolongation was detected. According to Bazett's formula, corrected QT was 504 ms. There were no published data about LADD syndrome with QT prolongation. This is the first case concerning LADD syndrome associated with QT prolongation. It is known that deafness and QT prolongation occur in potassium channel dysfunction. QT prolongation and deafness may be associated with potassium channel dysfunction in patients with LADD syndrome. As a result QT prolongation may be a new component of the LADD syndrome.
我们报告了一例检测出患有伴有QT间期延长的泪腺-耳-齿-指（LADD）综合征的小男孩。根据巴泽特公式，校正后的QT间期为504毫秒。目前尚无关于伴有QT间期延长的LADD综合征的公开数据。这是首例关于LADD综合征合并QT间期延长的病例。已知耳聋和QT间期延长发生于钾通道功能障碍。LADD综合征患者的QT间期延长和耳聋可能与钾通道功能障碍有关。因此，QT间期延长可能是LADD综合征的一个新组成部分。
