Bauerfeind P, Allemann A, Gyr N
Medizinische Klinik, Kantonsspital Liestal, Universität Basel, Schweiz.
Z Gastroenterol. 1992 Nov;30(11):791-4.
In 633 persons of the Madang province in Papua-New Guinea hookworm-infection, blood hemoglobin and the presence of blood in stools were studied. 60% of the subjects were infected with hookworm (Necator americanus). There was a significant linear correlation between the intensity of hookworm infection and blood haemoglobin level. The Colo-Rectal test gave positive results in 17% of the cases without worm-infection. In infected persons, the Colo-Rectal test gave an increasing rate of positive results as the parasite infection increased: 24% for subjects with low levels of infection, and 57% and 67% for moderate and high levels, respectively. The mean blood-haemoglobin level was lower in persons with positive Colo-Rectal-Test and hookworm infection (11.8 g%) than among those with negative Colo-Rectal-Test and hookworm infection (15.0 g%, p < 0.01). In young populations with a known high prevalence of hookworm infection, Colo-Rectal test is therefore suitable for the detection of moderate or severe hookworm infections. It may serve as a simple and useful method to work up anaemia is such populations.
在巴布亚新几内亚马当省的633人身上，研究了钩虫感染、血液血红蛋白以及粪便中血液的情况。60%的受试者感染了钩虫（美洲板口线虫）。钩虫感染强度与血液血红蛋白水平之间存在显著的线性相关性。在无蠕虫感染的病例中，结肠直肠检测呈阳性的比例为17%。在感染者中，随着寄生虫感染程度的增加，结肠直肠检测呈阳性的比例也增加：感染程度低的受试者为24%，中度和高度感染的受试者分别为57%和67%。结肠直肠检测呈阳性且感染钩虫的人的平均血液血红蛋白水平（11.8克%）低于结肠直肠检测呈阴性且感染钩虫的人（15.0克%，p<0.01）。因此，在已知钩虫感染率高的年轻人群中，结肠直肠检测适用于检测中度或重度钩虫感染。它可以作为一种简单且有用的方法来检查这类人群中的贫血情况。
