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[使用多普勒超声心动图对主动脉瓣狭窄严重程度进行无创定量和分类]

[Noninvasive quantification and classification of the severity of aortic stenosis using Doppler echocardiography].

作者信息

Schmalz A, Erbel R, Wittlich N, Mohr-Kahaly S, Meyer J

机构信息

II. Medizinische Klinik und Poliklinik, Johannes-Gutenberg-Universität Mainz.

出版信息

Z Kardiol. 1992 Nov;81(11):619-26.

PMID:1471399
Abstract

The exact determination of the severity of valvular heart disease represents the basis for the indication for surgery. Apart from the clinical findings, the estimation of the severity has, up to now, been based on the chest x-ray, the electrocardiogram, and the carotid pulse curve. By means of cardiac catheterization, the aortic valve gradient is determined and the aortic valve area is calculated using the Gorlin equation. Doppler echocardiography allows for a noninvasive gradient assessment. The peak and mean pressure gradients as well as the aortic valve area can be calculated. Echocardiography provides additional information about the severity of the left-ventricular hypertrophy, the heart size, as well as about secondary complications. Doppler echocardiography was performed in 95 patients to determine the peak pressure gradient. This Doppler-derived gradient correlated well with the catheterization-derived invasive gradient. The correlation coefficient was r = 0.81, for the mean gradient r = 0.77, and for the aortic valve area r = 0.87. Based on the classical determination of the severity of aortic stenosis by means of cardiac catheterization, a Doppler-derived mean pressure gradient > 54 mm Hg or a peak pressure gradient > 89 mm Hg and an aortic valve area > 0.7 cm2 are specific for severe aortic stenosis. A mean pressure gradient between 40 and 54 mm Hg or a peak pressure gradient of 67 and 89 mm Hg and an aortic valve area of 0.7 and 1.3 cm2 indicate moderately aortic stenosis.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

心脏瓣膜病严重程度的准确判定是手术指征的基础。除临床检查结果外,到目前为止,严重程度的评估还基于胸部X光、心电图和颈动脉脉搏曲线。通过心导管检查确定主动脉瓣压力阶差,并使用戈林公式计算主动脉瓣面积。多普勒超声心动图可进行无创压力阶差评估。可计算峰值和平均压力阶差以及主动脉瓣面积。超声心动图还能提供有关左心室肥厚严重程度、心脏大小以及继发性并发症的额外信息。对95例患者进行了多普勒超声心动图检查以确定峰值压力阶差。该多普勒衍生的压力阶差与心导管检查衍生的有创压力阶差相关性良好。相关系数分别为:峰值压力阶差r = 0.81,平均压力阶差r = 0.77,主动脉瓣面积r = 0.87。基于通过心导管检查对主动脉瓣狭窄严重程度的经典判定,多普勒衍生的平均压力阶差> 54 mmHg或峰值压力阶差> 89 mmHg且主动脉瓣面积> 0.7 cm²是重度主动脉瓣狭窄的特征。平均压力阶差在40至54 mmHg之间或峰值压力阶差在67至89 mmHg之间且主动脉瓣面积在0.7至1.3 cm²之间表明为中度主动脉瓣狭窄。(摘要截断于250字)

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