长期暴露于强光下时视网膜结构变化的动态过程。

Dynamics of structural changes in the retina during long-term exposure to bright light.

作者信息

Logvinov S V, Potapov A V, Varakuta E Yu, Drobatulina D A

机构信息

Department of Histology, Cytology, and Embryology, Siberian State Medical University, Tomsk.

出版信息

Bull Exp Biol Med. 2003 Oct;136(4):411-4. doi: 10.1023/b:bebm.0000010966.86664.b8.

DOI:10.1023/b:bebm.0000010966.86664.b8

PMID:14714097

Abstract

Exposure to high-intensity light led to pronounced destructive changes in the retina and focal loss of layers formed by neurosensory cells in rats. Photoinjury led to progressive decrease in the numerical density of nuclei in the outer nuclear layer (by 30% after 2 days, by 75% after 1 week, and more than by 90% after 2 weeks of exposure). After 30 days the photosensory layer completely disappeared, while the outer nuclear layer was presented by solitary nuclei of neurosensory cells.

摘要

暴露于高强度光线下会导致大鼠视网膜出现明显的破坏性变化以及神经感觉细胞形成的层状结构局部缺失。光损伤导致外核层细胞核的数量密度逐渐降低（暴露2天后降低30%，1周后降低75%，2周后降低超过90%）。30天后，光感受层完全消失，而外核层仅由神经感觉细胞的单个细胞核组成。