Tervonen S A, Stratmann U, Mokrys K, Reichart P A
Department of Oral Surgery and Dental Radiology, Universitätsmedizin Berlin, Charité, Campus Virchow Klinikum, Augustenburger Platz 1, 13353, Berlin, Germany.
Clin Oral Investig. 2004 Jun;8(2):45-51. doi: 10.1007/s00784-003-0245-0. Epub 2004 Jan 9.
Regional odontodysplasia (RO) is a rare dental anomaly involving both dentitions, mostly teeth of one quadrant. The characteristic findings are discolored soft teeth accompanied by gingivitis, swelling or abscess. Enamel and dentin are hypomineralised and hypoplastic, so that the 'ghost teeth' appear shadowy in radiographs with wide pulp chambers. The etiology is unknown. Epidemiological data is rare; 138 cases of RO have been published to date and reports on ultrastructure are few. An analysis of published cases of RO in the international literature is presented. The sex ratio of females to males was 1.7:1. The age at the time of diagnosis ranged between 4 and 23 years. The maxilla was more often affected (maxilla to mandible ratio 1.6:1). In 67 patients the deciduous and permanent dentitions were affected (47.1%). In 129 cases, affected teeth lay side by side. Missing tooth development was observed in 10.7%. Failure of tooth eruption of RO teeth occurred in 39.7%. In addition, four cases with RO which were collected over a period of more than 25 years are presented. Ultrastructural findings of one specimen are demonstrated.
区域牙发育异常（RO）是一种罕见的牙齿异常，累及乳牙列和恒牙列，多发生于一个象限的牙齿。其特征性表现为牙齿变色、质地软，并伴有牙龈炎、肿胀或脓肿。釉质和牙本质矿化不足且发育不全，因此在X线片上，“幽灵牙”的髓腔宽大，影像模糊。病因不明。流行病学数据罕见；迄今为止，已发表138例RO病例报告，而关于其超微结构的报道较少。本文对国际文献中已发表的RO病例进行分析。女性与男性的性别比为1.7:1。诊断时的年龄在4至23岁之间。上颌更常受累（上颌与下颌的比例为1.6:1）。67例患者的乳牙列和恒牙列均受累（47.1%）。129例中，受累牙齿相邻。观察到10.7%的患者存在牙齿发育缺失。39.7%的RO牙齿出现萌出失败。此外，还介绍了在超过25年的时间里收集到的4例RO病例。展示了其中一个标本的超微结构研究结果。
