Yoshioka Masato, Sato Tsutomu, Furuya Tomoki, Shibata Satoshi, Andoh Hideaki, Asanuma Yoshihiro, Hatazawa Jun, Koyama Kenji
Department of Surgery, Akita University School of Medicine, 1-1-1 Hondo, 010-8543 Akita, Japan.
J Gastroenterol. 2003;38(12):1189-93. doi: 10.1007/s00535-003-1230-8.
We used positron emission tomography with 2-deoxy-2-[(18)F]fluoro- d-glucose (FDG-PET) in the diagnosis of two cases of malignant intraductal papillary mucinous tumor (IPMT) of the pancreas. A 56-year-old man and a 72-year-old man, both with tumors in the pancreatic head, were referred to Akita University Medical Center. Computed tomography revealed tumors with multiple cystic components in both patients. FDG-PET images showed markedly high FDG uptake in the area corresponding to a solid component found in one patient and diffuse faint uptake, higher than that of the surrounding tissue, in the other patient, who had no solid component. Histological examination of the resected specimens after pancreatectomy showed invasive carcinoma involving the pancreatic parenchyma in both patients. Although our experience is limited and preliminary, FDG-PET seems to be useful for the detection of malignancy in IPMT, especially in patients not showing any solid component on conventional diagnostic images such as computed tomography.
我们使用2-脱氧-2-[(18)F]氟-D-葡萄糖正电子发射断层扫描（FDG-PET）对两例胰腺导管内乳头状黏液性恶性肿瘤（IPMT）进行诊断。一名56岁男性和一名72岁男性，两人胰腺头部均有肿瘤，被转诊至秋田大学医学中心。计算机断层扫描显示两名患者的肿瘤均有多个囊性成分。FDG-PET图像显示，一名患者中与实性成分相对应的区域有明显高的FDG摄取，另一名无实性成分的患者则有弥漫性淡摄取，高于周围组织。胰腺切除术后对切除标本进行组织学检查显示，两名患者均有累及胰腺实质的浸润性癌。尽管我们的经验有限且属初步，但FDG-PET似乎有助于检测IPMT中的恶性肿瘤，尤其是在传统诊断图像（如计算机断层扫描）上未显示任何实性成分的患者中。
