Bodani M, Kopelman M D
Adamson Centre for Mental Health, St Thomas' Hospital, London, UK.
Lupus. 2003;12(12):947-9. doi: 10.1191/0961203303lu507oa.
A brief description of psychosis in the general psychiatric setting and its treatment using antipsychotic agents including 'atypical' drugs. A review of the prevalence of neuropsychiatric syndromes in lupus (using The American College of Rheumatology standardized definitions) from recent studies showing wide variation in reported rates. Underlying pathophysiologic mechanisms postulated for neuropsychiatric manifestations of lupus are reviewed with implications for treatment. The use and success of intravenous pulsed cyclophosphamide (singly and in combination with methylprednisiolone) for severe neuropsychiatric psychosis is reviewed.
在普通精神科环境中对精神病的简要描述及其使用抗精神病药物（包括“非典型”药物）的治疗方法。对近期研究中狼疮神经精神综合征的患病率（使用美国风湿病学会标准化定义）进行综述，这些研究表明报告的发病率差异很大。对狼疮神经精神表现的潜在病理生理机制进行综述及其对治疗的影响。综述静脉注射脉冲环磷酰胺（单独使用以及与甲基泼尼松龙联合使用）治疗严重神经精神性精神病的应用及疗效。
