Zafar Haider, Takimoto Chris H, Weiss Geoffrey
Division of Medical Oncology, Department of Medicine, University of Texas Health Science Center at San Antonio, 7703 Floyd Curl Drive, San Antonio, TX 78229, USA.
Med Oncol. 2003;20(4):403-8. doi: 10.1385/MO:20:4:403.
We report a case of recurrent solitary fibrous tumor with associated hypoglycemia, the "Doege-Potter syndrome." These are rare tumors with a 12-13% rate of malignancy. The syndrome of hypoglycemia is seen in less than 5% of the cases, and the associated tumors are large with a high mitotic rate. The cause of hypoglycemia is related to insulin-like growth factors produced by these tumors. Resection in many cases is curable with resolution of the hypoglycemia. We discuss the different signs and symptoms and literature evidence of treatment options and follow-up.
我们报告了一例伴有低血糖的复发性孤立性纤维瘤，即“多伊格-波特综合征”。这些是罕见肿瘤，恶性率为12%-13%。低血糖综合征在不到5%的病例中可见，且相关肿瘤体积大、有丝分裂率高。低血糖的病因与这些肿瘤产生的胰岛素样生长因子有关。在许多病例中，手术切除可治愈并缓解低血糖。我们讨论了不同的体征和症状以及治疗选择和随访的文献证据。
