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胃肠道间质瘤孤立性腹部伤口转移

Isolated abdominal wound metastasis from a gastrointestinal stromal tumor.

作者信息

Cunningham Steven C, Shibata David, Volpe Carmine

机构信息

Division of Surgical Oncology, Department of Surgery, University of Maryland Medical System, 22 South Greene Street, Baltimore, MD 21201, USA.

出版信息

Int J Gastrointest Cancer. 2003;33(2-3):129-32. doi: 10.1385/IJGC:33:2-3:129.

DOI:10.1385/IJGC:33:2-3:129
PMID:14716061
Abstract

BACKGROUND

Gastrointestinal stromal tumors (GIST) frequently recur even after complete resection. The typical pattern of failure from GISTs is both local and distant with hepatic and peritoneal metastases being most common. Isolated abdominal-wall recurrence from GISTs has not been previously described.

AIM OF THE STUDY

To report an isolated abdominal-wound recurrence in the absence of widespread disease in a patient with GIST.

METHODS

Case report of a GIST and isolated abdominal-wound recurrence after laparoscopic-assisted en bloc resection.

RESULTS

Elderly male patient presented with an isolated abdominal wall incisional recurrence 18 mo after gastric resection and adjuvant imatinib mesylate therapy for a high-grade GIST.

CONCLUSIONS

Complete resection of gastrointestinal stromal tumors followed by imatinib therapy may alter the extent of recurrence.

摘要

背景

胃肠道间质瘤(GIST)即使在完全切除后也经常复发。GIST典型的复发模式是局部和远处复发,肝转移和腹膜转移最为常见。此前尚未有关于GIST孤立性腹壁复发的报道。

研究目的

报告1例GIST患者在无广泛病变情况下出现的孤立性腹部伤口复发。

方法

1例GIST患者腹腔镜辅助整块切除术后出现孤立性腹部伤口复发的病例报告。

结果

老年男性患者,因高级别GIST行胃切除及辅助甲磺酸伊马替尼治疗18个月后出现孤立性腹壁切口复发。

结论

胃肠道间质瘤完全切除后联合伊马替尼治疗可能会改变复发程度。

相似文献

1
Isolated abdominal wound metastasis from a gastrointestinal stromal tumor.胃肠道间质瘤孤立性腹部伤口转移
Int J Gastrointest Cancer. 2003;33(2-3):129-32. doi: 10.1385/IJGC:33:2-3:129.
2
Giant malignant gastrointestinal stromal tumors: recurrence and effects of treatment with STI-571.巨大恶性胃肠道间质瘤:复发及STI-571治疗的效果
World J Gastroenterol. 2005 Jan 14;11(2):260-3. doi: 10.3748/wjg.v11.i2.260.
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J Nucl Med. 2004 Jan;45(1):17-21.
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Successful resection of a giant recurrent gastrointestinal stromal tumour with imatinib mesylate as neoadjuvant therapy.以甲磺酸伊马替尼作为新辅助治疗成功切除巨大复发性胃肠道间质瘤。
Scand J Gastroenterol. 2007 Sep;42(9):1138-40. doi: 10.1080/00365520701206779.
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Ann Surg Oncol. 2013 Feb;20(2):586-92. doi: 10.1245/s10434-012-2647-1. Epub 2012 Sep 11.
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Surgical resection of gastrointestinal stromal tumors after treatment with imatinib.伊马替尼治疗后胃肠道间质瘤的手术切除
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[New surgical approaches to localized and advanced gastrointestinal stromal tumors (GIST)].[针对局限性和晚期胃肠道间质瘤(GIST)的新手术方法]
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本文引用的文献

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The GIST of targeted cancer therapy: a tumor (gastrointestinal stromal tumor), a mutated gene (c-kit), and a molecular inhibitor (STI571).靶向癌症治疗的要点:一种肿瘤(胃肠道间质瘤)、一个突变基因(c-kit)和一种分子抑制剂(STI571)。
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Port site metastasis after diagnostic laparoscopy for upper gastrointestinal tract malignancies: an uncommon entity.
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Imatinib mesylate--a new oral targeted therapy.甲磺酸伊马替尼——一种新型口服靶向治疗药物。
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