Iteen S A, Ceppaglia J
Drug Technology Assessment Program, UCI Medical Center, Orange 92668.
Am J Hosp Pharm. 1992 Nov;49(11):2746-8.
A hospitalwide computer system that combines protocol-specific information on investigational drugs with order entry is described. A large university teaching hospital had in place a computerized clinical information system. Among other uses, physicians used the system for direct entry of total parenteral nutrient solution orders and associated laboratory tests; labels are produced automatically. Personnel from the pharmacy and information services departments met to discuss how to apply the computer system to investigational drug information. The application they designed has three components: protocol information, order entry, and patient monitoring. Protocol information, including all the standard drug data plus regulatory and investigator information, is displayed as a report on the user's terminal. The order-entry pathway allows the research pharmacist to predesign medication labels that are specific to each study and include all required information. This saves time, ensures accurate labeling, and provides a means for generating patient charges. The patient-monitoring component provides information to the research pharmacist in a daily report to assist in locating subject patients and to monitor compliance with protocols. The system has improved the access of health-care professionals to investigational drug information and decreased the time pharmacists spend dispensing these agents. The system has been well received, although up to three weeks is needed to bring the information online. A hospitalwide information system is effective in disseminating information on investigational drugs and facilitating order entry.
本文描述了一种全院范围的计算机系统，该系统将研究性药物的特定方案信息与医嘱录入相结合。一所大型大学教学医院已经配备了计算机化临床信息系统。在其他用途中，医生使用该系统直接录入全胃肠外营养溶液医嘱及相关实验室检查；标签会自动生成。药学和信息服务部门的人员会面讨论如何将计算机系统应用于研究性药物信息。他们设计的应用程序有三个组成部分：方案信息、医嘱录入和患者监测。方案信息，包括所有标准药物数据以及监管和研究者信息，会作为一份报告显示在用户终端上。医嘱录入途径允许研究药师预先设计针对每项研究的用药标签，并包含所有所需信息。这节省了时间，确保标签准确无误，并提供了生成患者费用的手段。患者监测组件在每日报告中向研究药师提供信息，以协助查找受试患者并监测方案的依从性。该系统改善了医护人员获取研究性药物信息的途径，减少了药师调配这些药物所花费的时间。尽管需要长达三周的时间才能使信息上线，但该系统受到了广泛好评。全院范围的信息系统在传播研究性药物信息和促进医嘱录入方面是有效的。
