Personne Mark, Mansten Anders, Svensson Jan-Olof
Giftinformationscentralen, Stockholm.
Lakartidningen. 2003 Dec 11;100(50):4194-5.
A 66-year old man called for an ambulance from his home because of acute chest pain. When the crew arrived he was unresponsive and hypotensive. Sublingual nitroglycerine was given and subsequently the patient collapsed into circulatory failure and respiratory arrest. He was intubated and transported to the nearest hospital. The severe hypotension was combated with fluids and norepinephrine. During the next few hours his skin gradually turned intensely yellow, as did the urine. Acute myocardial infarction also occurred and renal failure developed. The cause of the neon-yellow colour was a complete mystery until a police patrol sent to his apartment found several empty packages of dipyridamole (Persantin Depot) corresponding to 34 g, an overdose seven times higher than any previous case reported in the literature. This drug has a distinct yellowish colour. The patient's condition gradually improved and he could be extubated within a week. Haemodialysis was needed for two weeks because of acute tubular necrosis after the prolonged period of hypotension, but thereafter he recovered.
一名66岁男子因急性胸痛从家中呼叫救护车。医护人员赶到时，他已无反应且血压过低。给予了舌下硝酸甘油，随后患者陷入循环衰竭和呼吸骤停。他被插管并送往最近的医院。通过补液和去甲肾上腺素对抗严重的低血压。在接下来的几个小时里，他的皮肤逐渐变得极度发黄，尿液也是如此。还发生了急性心肌梗死并出现肾衰竭。这种霓虹黄色的原因完全成谜，直到派往他公寓的警察巡逻队发现了几包共34克的双嘧达莫（潘生丁长效制剂）空包装，这一过量剂量比文献中此前报道的任何病例都高出七倍。这种药物有明显的淡黄色。患者的病情逐渐好转，一周内即可拔管。由于长时间低血压后出现急性肾小管坏死，需要进行两周的血液透析，但此后他康复了。
