Schalow G, Pääsuke M, Ereline J, Gapeyeva H
Institute of Exercise Biology and Physiotherapy, University of Tartu, 5 Jakobi Street, Tartu 51014, Estonia.
Electromyogr Clin Neurophysiol. 2003 Dec;43(8):473-85.
Coordination dynamics were measured in Parkinson's disease patients to quantify central nervous system (CNS) dysfunction. The low-load coordination dynamics in the patients were impaired by 56% for forward and 44% for backward moving in comparison to a control group of similar age. Exercising at higher load was only partly possible. When the disease preferentially affected one side of the body, the coordination dynamics were worse for the affected side. A dexterity test showed that coordination of hand and arm movements could be improved in the short-term memory when exercising on the special coordination dynamics recording and therapy device. Simultaneously taken surface EMG (sEMG) showed that the motor pattern was impaired in the Parkinson's disease patients. sEMG recordings showed further that the fast fatigable muscle fibre activation was impaired. FF-type muscle fibres were already activated for low load in one and not at all in another muscle. In conclusion, coordination between motoneuron firings and between arm and leg movements were found to be impaired in Parkinson's disease patients.
对帕金森病患者的协调动力学进行了测量，以量化中枢神经系统（CNS）功能障碍。与年龄相仿的对照组相比，患者的低负荷协调动力学在向前移动时受损56%，向后移动时受损44%。在较高负荷下进行锻炼仅部分可行。当疾病优先影响身体一侧时，受影响一侧的协调动力学更差。一项灵巧性测试表明，在特殊的协调动力学记录和治疗设备上进行锻炼时，手部和手臂运动的协调在短期记忆中可以得到改善。同时采集的表面肌电图（sEMG）显示，帕金森病患者的运动模式受损。sEMG记录进一步显示，快速疲劳性肌纤维激活受损。在一块肌肉中，FF型肌纤维在低负荷时就已被激活，而在另一块肌肉中则完全未被激活。总之，发现帕金森病患者运动神经元放电之间以及手臂和腿部运动之间的协调受损。
