Dolo A, Camara F, Poudiougo B, Touré A, Kouriba B, Bagayogo M, Sangaré D, Diallo M, Bosman A, Modiano D, Touré Y T, Doumbo O
Dép. d'épidémiologie des affections parasitaires, Faculté de médecine, de pharmacie et d'odonto-stomalogie, BP 1805, Bamako, Mali.
Bull Soc Pathol Exot. 2003 Nov;96(4):308-12.
We carried out five cross sectional surveys between 1993 and 1994 to assess the epidemiology of malaria in the village of Bancoumana, located in the Sudanese savannah areas of Mali. Each survey included a collection of entomological, clinical, parasitological and immunological data. The study population involved 1600 children from six months to 9 years of age. The main vector was Anopheles gambiae s.l., man bite rate and entomological inoculation rate were maximum respectively in August (peak of the transmission season) and October (end of transmission season). Plasmodium. falciparum was the main parasite species observed. Spleen enlargement rate, parasite rate, gametocyte rate and parasite density varied significantly with age and season. The parasite rate, gametocyte rate and parasite density were significantly low in October 1994 compared with October 1993 while the entomologic parameter did not show any variation over the two years. This reduction of parasitologic index between 1993 and 1994 may be related to an increase of anti-malarial drug use in the population. Our results show that malaria is hyperendemic in the village of Bancoumana.
1993年至1994年间，我们开展了五次横断面调查，以评估位于马里苏丹草原地区的班库马纳村的疟疾流行病学情况。每次调查都包括收集昆虫学、临床、寄生虫学和免疫学数据。研究人群包括1600名年龄在6个月至9岁之间的儿童。主要病媒是冈比亚按蚊复合组，人均被叮咬率和昆虫学接种率分别在8月（传播季节高峰期）和10月（传播季节末期）达到最高。恶性疟原虫是观察到的主要寄生虫种类。脾肿大率、寄生虫感染率、配子体率和寄生虫密度随年龄和季节有显著变化。与1993年10月相比，1994年10月的寄生虫感染率、配子体率和寄生虫密度显著降低，而昆虫学参数在这两年间没有任何变化。1993年至1994年间寄生虫学指标的这种下降可能与人群中抗疟药物使用增加有关。我们的结果表明，班库马纳村疟疾高度流行。
