Boudin C, Robert V
IRD-UR paludisme afro-tropical, Laboratoire de paludologie, B.P. 1386, Dakar, Sénégal.
Bull Soc Pathol Exot. 2003 Nov;96(4):335-40.
The level of malaria transmission is usually estimated by some entomological parameters (entomological inoculation rate or reproductive rate and its seasonal variations). However, only one aspect of the malaria transmission is explored by this way, i.e. the transmission of Plasmodium from mosquito to man. The transmission from man to mosquito, the development of parasite in the mosquito midgut, and the role of transmission blocking immunity remain poorly documented. Recent studies on vaccination with gamete antigens showed that transmission blocking immunity, and the natural infectiousness of gametocytes after treatment underlined the need for taking into account a new aspect of malaria epidemiology concerning the transmission of Plasmodium from man to mosquito. In this paper, authors propose and discuss different new indicators and methods to improve our knowledge on malaria epidemiology.
疟疾传播水平通常由一些昆虫学参数（昆虫接种率或繁殖率及其季节变化）来估计。然而，通过这种方式仅探讨了疟疾传播的一个方面，即疟原虫从蚊子到人的传播。从人到蚊子的传播、寄生虫在蚊子中肠的发育以及传播阻断免疫的作用仍记录不足。最近关于配子抗原疫苗接种的研究表明，传播阻断免疫以及治疗后配子体的自然传染性凸显了有必要考虑疟疾流行病学中关于疟原虫从人到蚊子传播的一个新方面。在本文中，作者提出并讨论了不同的新指标和方法，以增进我们对疟疾流行病学的了解。
