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胸骨后甲状腺肿:手术治疗的安全性

Retrosternal goiters: safety of surgical treatment.

作者信息

Parra-Membrives Pablo, Sánchez-Blanco José Miguel, Gómez-Rubio Diego, Recio-Moyano Gumersindo, Diaz-Roldán Jorge

机构信息

Department of General and Digestive Surgery, Hospital Universitario de Valme, Sevilla, Spain.

出版信息

Int Surg. 2003 Oct-Dec;88(4):205-10.

PMID:14717526
Abstract

Retrosternal goiters still pose a problem to expert endocrine surgeons. Whether surgery should be the treatment of choice or not remains controversial because of hypothetical increased morbidity rates associated with the surgical approach. Eighty-three patients were retrospectively reviewed for anesthetic risk, fibrobronchoscopic guidance for intubation, surgical technique, mortality and morbidity rates, and pathological findings. We found 6.09% of American Society of Anesthesiologists (ASA) I, 41.46% of ASA II, 40.24% of ASA III, and 12.19% of ASA IV risk. Twelve patients (14.45%) required fibrobronchoscopic guidance for intubation. Only one patient required a sternotomy. No mortality occurred. Seven patients (8.43%) had major complications, but there were no instances of permanent recurrent laryngeal palsy or hypocalcemia. Pathological examination revealed 9.63% incidence of malignancy. Surgery should be the treatment of choice for retrosternal goiters because there is a significant incidence of malignancy and an acceptable morbidity rate.

摘要

胸骨后甲状腺肿仍然给专业内分泌外科医生带来难题。由于手术方式可能导致发病率增加,手术是否应作为首选治疗方法仍存在争议。回顾性分析了83例患者的麻醉风险、纤维支气管镜引导插管、手术技术、死亡率和发病率以及病理结果。我们发现美国麻醉医师协会(ASA)I级风险的患者占6.09%,ASA II级风险的占41.46%,ASA III级风险的占40.24%,ASA IV级风险的占12.19%。12例患者(14.45%)需要纤维支气管镜引导插管。仅1例患者需要进行胸骨切开术。无死亡病例。7例患者(8.43%)发生了严重并发症,但无永久性喉返神经麻痹或低钙血症病例。病理检查显示恶性肿瘤发生率为9.63%。由于胸骨后甲状腺肿有显著的恶性肿瘤发生率且发病率可接受,手术应作为其首选治疗方法。

相似文献

1
Retrosternal goiters: safety of surgical treatment.胸骨后甲状腺肿:手术治疗的安全性
Int Surg. 2003 Oct-Dec;88(4):205-10.
2
Management of retrosternal goiters: experience of a surgical unit.胸骨后甲状腺肿的管理:一个外科单位的经验
Int Surg. 2005 Apr-Jun;90(2):61-5.
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Morbidity and mortality of thyroidectomy for substernal goiter.胸骨后甲状腺肿手术的发病率和死亡率。
Head Neck. 2010 Jun;32(6):744-9. doi: 10.1002/hed.21246.
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[Substernal goitre. Personal experience].[胸骨后甲状腺肿。个人经验]
Ann Ital Chir. 2005 Nov-Dec;76(6):517-21; discussion 521-2.
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Increased mortality and morbidity associated with thyroidectomy for intrathoracic goiters reaching the carina tracheae.因累及气管隆突的胸内甲状腺肿行甲状腺切除术导致死亡率和发病率增加。
Arch Surg. 2006 Jan;141(1):82-5. doi: 10.1001/archsurg.141.1.82.
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Surgical management of substernal goiters: clinical experience of 170 cases.胸骨后甲状腺肿的外科治疗:170例临床经验
Surg Today. 2004;34(9):732-6. doi: 10.1007/s00595-004-2823-4.
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Substernal goiters: incidence, surgical approach, and complications in a tertiary care referral center.胸骨后甲状腺肿:发生率、手术入路和三级医疗转诊中心的并发症。
Head Neck. 2011 Oct;33(10):1420-5. doi: 10.1002/hed.21617. Epub 2010 Nov 10.
8
Substernal goiters and sternotomy.胸骨后甲状腺肿与胸骨切开术
Laryngoscope. 2009 Apr;119(4):683-8. doi: 10.1002/lary.20102.
9
Surgical management of substernal goiter: analysis of 237 patients.胸骨后甲状腺肿的手术治疗:237例患者分析
Am Surg. 1995 Sep;61(9):826-31.
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Retrosternal goiters.胸骨后甲状腺肿
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引用本文的文献

1
Surgical treatment of large substernal thyroid goiter: analysis of 12 patients.巨大胸骨后甲状腺肿的外科治疗:12例患者分析
Int J Clin Exp Med. 2013 Aug 1;6(7):488-96. Print 2013.
2
Surgical treatment of substernal goiter: an analysis of 59 patients.胸骨后甲状腺肿的外科治疗:59例患者分析
Surg Today. 2008;38(6):505-11. doi: 10.1007/s00595-007-3659-5. Epub 2008 May 31.
3
Evidence-based surgical management of substernal goiter.胸骨后甲状腺肿的循证外科治疗
World J Surg. 2008 Jul;32(7):1285-300. doi: 10.1007/s00268-008-9466-3.
4
Effect of hospital volume of thyroidectomies on outcomes following substernal thyroidectomy.甲状腺切除术的医院手术量对胸骨后甲状腺切除术后结局的影响。
World J Surg. 2008 May;32(5):740-6. doi: 10.1007/s00268-007-9347-1.