Koizumi Minako, Hagino Daisuke, Fukuyama Chiyoko, Abe Kanako, Inoue Kumiko, Arai Yuko, Takechi Kimihiro
Ibaraki Prefectural Central Hospital, Ibaraki, Japan.
J Obstet Gynaecol Res. 2004 Feb;30(1):37-41. doi: 10.1111/j.1341-8076.2004.00153.x.
The clinical features of Schönlein-Henoch Purpura (SHP) consist of non-thrombocytopenic purpura in association with joint, gastrointestinal and renal involvements. Because it is uncommon in adults, there is little information on the effects of SHP on pregnancy in the literature. This report documents the clinical findings and outcome of an uncommon case of SHP affecting a woman who was 25 weeks pregnant. Prompt steroid-therapy induced a rapidly favorable course and successful vaginal delivery at 40 weeks gestation. If SHP develops during pregnancy, it is not always easy to distinguish from obstetrical complications such as pre-eclampsia. An early diagnosis is important especially if renal involvement exists, because the prognosis for this disease can include nephropathy and it therefore needs close monitoring.
过敏性紫癜(SHP)的临床特征包括非血小板减少性紫癜,并伴有关节、胃肠道和肾脏受累。由于其在成人中并不常见,文献中关于SHP对妊娠影响的信息很少。本报告记录了一例罕见的SHP病例的临床发现及结果,该病例发生在一名怀孕25周的女性身上。及时使用类固醇治疗导致病情迅速好转,并在妊娠40周时成功进行了阴道分娩。如果在怀孕期间发生SHP,有时很难与诸如子痫前期等产科并发症区分开来。早期诊断尤为重要,特别是在存在肾脏受累的情况下,因为这种疾病的预后可能包括肾病,因此需要密切监测。