Miller Nancy, Bushhouse Sally
School of Public Health, and Department of Orthopedic Surgery, University of Minnesota, USA.
Minn Med. 2003 Dec;86(12):26-31.
Breast-conserving surgery (BCS) followed by radiation is an accepted alternative to mastectomy for treatment of early-stage breast cancer. This study evaluated age-group, geographic, and cancer-stage variables associated with the likelihood of receiving BCS or receiving mastectomy and the likelihood of receiving radiation therapy following BCS. Minnesota Cancer Surveillance System data on 6,594 women diagnosed with breast cancer in Minnesota during the years 1995-1996 were analyzed. Of those women who underwent breast cancer surgeries, 39% received BCS. Seventy-two percent of cases in which BCS was used were followed by radiotherapy. Women 65 years and older were less likely than younger women to receive BCS. Age and the stage of the cancer were independently associated with the likelihood of receiving radiation therapy following BCS. Breast cancer patients 75 years and older were 73% less likely to receive radiation following BCS than patients ages 40 to 49. Radiation following BCS was more likely among women in the Twin Cities metropolitan area and south central Minnesota than among women in other regions.
保乳手术（BCS）联合放疗是早期乳腺癌治疗中一种可接受的乳房切除术替代方案。本研究评估了与接受保乳手术或乳房切除术的可能性以及保乳手术后接受放射治疗的可能性相关的年龄组、地理区域和癌症分期变量。分析了明尼苏达癌症监测系统中1995年至1996年期间在明尼苏达州被诊断为乳腺癌的6594名女性的数据。在接受乳腺癌手术的女性中，39%接受了保乳手术。在使用保乳手术的病例中，72%随后接受了放射治疗。65岁及以上的女性比年轻女性接受保乳手术的可能性更小。年龄和癌症分期与保乳手术后接受放射治疗的可能性独立相关。75岁及以上的乳腺癌患者保乳手术后接受放射治疗的可能性比40至49岁的患者低73%。与其他地区的女性相比，双子城大都市区和明尼苏达州中南部的女性保乳手术后接受放射治疗的可能性更大。
