通过自组装实现无规共聚物的一步多功能化

One-step multifunctionalization of random copolymers via self-assembly.

作者信息

Pollino Joel M, Stubbs Ludger P, Weck Marcus

机构信息

School of Chemistry and Biochemistry, Georgia Institute of Technology, Atlanta, Georgia 30332-0400, USA.

出版信息

J Am Chem Soc. 2004 Jan 21;126(2):563-7. doi: 10.1021/ja0372715.

DOI:10.1021/ja0372715

PMID:14719954

Abstract

A novel methodology for random copolymer functionalization based on a noncovalent, one-step, multifunctionalization strategy has been developed. Random copolymers possessing both palladated-pincer complexes and diaminopyridine moieties (hydrogen-bonding entities) have been synthesized using ring-opening metathesis polymerization. Noncovalent functionalization of the resultant copolymers is accomplished via (1) directed self-assembly, (2) multistep self-assembly, and (3) one-step orthogonal self-assembly. This system shows complete specificity of each recognition motif for its complementary unit, with no observable changes in the association constants regardless of the degree of functionalization.

摘要

基于非共价、一步法、多功能化策略，开发了一种用于无规共聚物功能化的新方法。使用开环易位聚合合成了同时具有钯化钳形配合物和二氨基吡啶部分（氢键实体）的无规共聚物。所得共聚物的非共价功能化通过（1）定向自组装、（2）多步自组装和（3）一步正交自组装来完成。该系统显示出每个识别基序对其互补单元具有完全特异性，无论功能化程度如何，缔合常数均无明显变化。