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热性惊厥婴儿的脑脊液葡萄糖浓度及对乙酰氨基酚的可能影响

CSF Glucose Concentrations in Infants with Febrile Convulsions and the Possible Effect of Acetaminophen.

作者信息

Mohammadi Mahmoud, Mohebbi Mohammad R, Naderi Fariba

机构信息

Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran.

出版信息

Indian Pediatr. 2003 Dec;40(12):1183-6.

PMID:14722369
Abstract

The present study was done to explore the relationship between the cerebrospinal fluid (CSF) glucose concentration, body temperature, seizure duration, and acetaminophen administration. Retrospective record review of 117 consecutive febrile convulsive infants aging 3 to 18 months admitted to Bahrami Children Hospital were studied. There was a positive correlation between CSF glucose level and body temperature in those who had not taken acetaminophen before admission (r = 0.515, n = 83). CSF glucose levels were significantly higher (P = 0.014) in febrile children (75.33 mg/dL, n =70) as compared with afebrile children (66.16 mg/dL, n = 13). In those administered acetaminophen there was a negative correlation between the CSF glucose level and body temperature (r = - 0.389, P = 0.023, n = 34). CSF glucose concentration was not significantly different (P = 0.076) in those who had taken acetaminophen than those who had not taken. Type of febrile seizure, fever, convulsion duration and multiplicity were not significantly correlated with CSF glucose concentration.

摘要

本研究旨在探讨脑脊液(CSF)葡萄糖浓度、体温、惊厥持续时间和对乙酰氨基酚给药之间的关系。对连续入住巴赫拉米儿童医院的117名3至18个月的热性惊厥婴儿进行回顾性记录审查。在入院前未服用对乙酰氨基酚的患者中,脑脊液葡萄糖水平与体温呈正相关(r = 0.515,n = 83)。与无热儿童(66.16 mg/dL,n = 13)相比,发热儿童(75.33 mg/dL,n = 70)的脑脊液葡萄糖水平显著更高(P = 0.014)。在服用对乙酰氨基酚的患者中,脑脊液葡萄糖水平与体温呈负相关(r = - 0.389,P = 0.023,n = 34)。服用对乙酰氨基酚的患者与未服用的患者相比,脑脊液葡萄糖浓度无显著差异(P = 0.076)。热性惊厥类型、发热、惊厥持续时间和发作次数与脑脊液葡萄糖浓度无显著相关性。

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