Briceno Pedro J, Ortiz Jorge A, Manzarbeitia Cosme, Jeon Hoonbae, Munoz Santiago J, Rothstein Kenneth D, Araya Victor, Gala Indira, Reich David J
Department of Surgery, Albert Einstein Medical Center, Philadelphia, PA 19141, USA.
Transplantation. 2004 Jan 15;77(1):137-9. doi: 10.1097/01.TP.0000101510.01404.F0.
The shortage of organs for liver transplantation has forced transplant centers to expand the donor pool by using donors traditionally labeled as marginal. One such example is liver transplantation using a donor with HELLP syndrome (hemolysis, elevated liver enzymes, and low platelets), a disorder of late pregnancy that involves the liver as one of the target organs.
Two patients who died from complications of HELLP syndrome were evaluated for attempted multi-organ procurement. Donor characteristics, gross and microscopic liver findings, and procurement and transplant outcomes were reviewed.
One of the liver allografts was successfully transplanted; the other was not procured because of poor macroscopic appearance.
It is possible to successfully transplant the liver from a donor that succumbs to HELLP syndrome, provided there is adequate recovery of liver function before procurement.
肝移植供体器官的短缺迫使移植中心通过使用传统上被视为边缘供体的方式来扩大供体库。其中一个例子是使用患有HELLP综合征（溶血、肝酶升高和血小板减少）的供体进行肝移植，HELLP综合征是一种妊娠晚期疾病，肝脏是其靶器官之一。
对两名死于HELLP综合征并发症的患者进行了多器官获取尝试评估。回顾了供体特征、肝脏大体和显微镜检查结果以及获取和移植结果。
其中一个肝移植器官成功移植；另一个因外观不佳未进行获取。
如果在获取前肝功能有足够恢复，那么死于HELLP综合征的供体肝脏有可能成功移植。
