Szodoray Péter, Bacskó György, Lakos Gabriella, Zeher Margit
Debreceni Egyetem, Orvos- és Egészségtudományi Centrum III. Belgyógyászati Klinika, Klinikai Immunológia Tanszék.
Orv Hetil. 2003 Dec 7;144(49):2411-3.
Patients with antiphospholipid syndrome have a high frequency of mid-pregnancy intrauterine growth retardation or fetal death. The authors report the case of a 28 year old pregnant woman with antiphospholipid syndrome with severe obstetrical complications (spontaneous abortion, missed abortion) in the past history. By means of the administration of combined immunomudulant (intravenous immunoglobulin, steroid), anticoagulant and antiplatelet therapy we could prevent a subsequent pregnancy loss of the patient. Apropos of this case the authors give an overview on the monitoring of the disease and the therapeutical recommendations of the literature.
抗磷脂综合征患者在孕中期出现胎儿宫内生长受限或胎儿死亡的频率较高。作者报告了一例28岁的抗磷脂综合征孕妇病例，其既往有严重产科并发症（自然流产、稽留流产）史。通过联合使用免疫调节剂（静脉注射免疫球蛋白、类固醇）、抗凝剂和抗血小板治疗，我们成功预防了该患者随后的妊娠丢失。关于该病例，作者对疾病监测及文献中的治疗建议进行了概述。
