Boonluksiri Pairoj
Pediatric Department, 182 Hatyai Hospital, Hatyai, Songkhla, Thailand.
J Trop Pediatr. 2003 Dec;49(6):379-81. doi: 10.1093/tropej/49.6.379.
The aim of the study was to determine seizure recurrence rate and risk factors of a first unprovoked seizure in children. Ninety-one children aged 2 months-15 years who had a first unprovoked seizure were enrolled and followed-up. History and physical examination were undertaken. The results were displayed as a Kaplan-Meier survival curve. Multivariate analysis was performed with Cox proportional-hazards model. The cumulative probability of recurrence rate was 68 per cent and incidence density was 6.85 per 100 person-months. The cumulative risk of recurrence was 50 per cent at 4 months and 66 per cent at 12 months. No risk of seizure recurrence was found in this study.
该研究的目的是确定儿童首次无诱因癫痫发作的复发率和危险因素。纳入91名年龄在2个月至15岁之间首次出现无诱因癫痫发作的儿童并进行随访。进行了病史和体格检查。结果以Kaplan-Meier生存曲线呈现。采用Cox比例风险模型进行多变量分析。复发率的累积概率为68%，发病密度为每100人月6.85例。4个月时复发的累积风险为50%，12个月时为66%。本研究未发现癫痫复发风险。
