Daniel C Ralph, Piraccini Bianca Maria, Tosti Antonella
Department of Medicine, University of Missisippi Medical Center, Jackson, Mississippi, USA.
J Am Acad Dermatol. 2004 Feb;50(2):258-61. doi: 10.1016/j.jaad.2003.06.008.
Drugs, chemicals, and biological substances accumulate and are stored in hair and nails where they can be detected and measured. Advantages of analyzing hair and nail samples also include their easy and non-invasive collection, the small sample size required for analysis, and their easy storage at room temperature. We report 3 examples of heavy metal poisoning diagnosed because of the hair or nail symptoms. Drugs and toxins that can be detected in hair and nails are reviewed and the application of hair/nail analysis in general and in forensic medicine is discussed.
药物、化学物质和生物物质会在头发和指甲中蓄积并储存起来,在这些部位可以对它们进行检测和测量。分析头发和指甲样本的优势还包括样本采集简便、无创,分析所需样本量小,以及易于在室温下保存。我们报告了3例因头发或指甲症状而诊断出的重金属中毒病例。对可在头发和指甲中检测到的药物和毒素进行了综述,并讨论了头发/指甲分析在一般医学和法医学中的应用。