Sudhakar Selvin S, Ross John J
Division of Infectious Diseases, Caritas Saint Elizabeth's Medical Center, Boston, MA 02135, USA.
Clin Infect Dis. 2004 Feb 1;38(3):444-7. doi: 10.1086/381099. Epub 2004 Jan 13.
Recommendations for prolonged penicillin treatment of actinomycosis date from the early antibiotic era, when patients often presented with neglected, advanced disease and received interrupted therapy at suboptimal dosages. This report describes cases of esophageal and of cervicofacial actinomycosis treated successfully with short-term antibiotic therapy and reviews the literature. Many patients are cured with <6 months of antibiotic therapy. If short-term antibiotic treatment is attempted, the clinical and radiological response should be closely monitored. Cervicofacial actinomycosis is especially responsive to brief courses of antibiotic treatment.
关于放线菌病长期青霉素治疗的建议可追溯到抗生素时代早期，当时患者常表现为被忽视的晚期疾病，并接受剂量不足且间断的治疗。本报告描述了采用短期抗生素治疗成功治愈的食管和颈面部放线菌病病例，并对相关文献进行了综述。许多患者通过<6个月的抗生素治疗得以治愈。若尝试进行短期抗生素治疗，应密切监测临床和影像学反应。颈面部放线菌病对短期抗生素治疗尤为敏感。
