Takase Yasushi, Nakano Misa, Tatsumi Chikao
Department of Neurology, Toyonaka Municipal Hospital.
Rinsho Shinkeigaku. 2003 Sep;43(9):533-8.
Although the primary chronic daily headache is subdivided into chronic migraine, chronic tension-type headache, hemicrania continua, and new daily persistent headache (NDPH), the characteristics of NDPH have not been well studied in Japan. The purpose of this study is to investigate the clinical characteristics of the primary NDPH. Twenty-one men and twenty-two women with primary NDPH, aged 14 to 73 years were diagnosed at Toyonaka Municipal Hospital from November 1997 to April 2003. Age of the onset ranged from 13 to 73 years (mean, 34.8). The onset of headache occurred in relation to a stressful life event in 16%, a systemic infection in 12% and an extracranial surgery in 7%. Any precipitating events could not be identified in approximately two-third of patients (65%). Quality of the headache was described as dull and/or pressure-like sensation in 91%, throbbing and/or pulsating sensation in 28%. NDPH needs further study, because it appears to be one of the most refractory headaches.
尽管原发性慢性每日头痛可细分为慢性偏头痛、慢性紧张型头痛、持续性偏侧头痛和新发性每日持续性头痛（NDPH），但在日本对NDPH的特征尚未进行充分研究。本研究的目的是调查原发性NDPH的临床特征。1997年11月至2003年4月期间，丰中市立医院诊断出21名男性和22名女性患有原发性NDPH，年龄在14至73岁之间。发病年龄为13至73岁（平均34.8岁）。16%的头痛发作与生活应激事件有关，12%与全身感染有关，7%与颅外手术有关。约三分之二的患者（65%）无法确定任何诱发事件。91%的患者将头痛的性质描述为钝痛和/或压迫样感觉，28%的患者描述为搏动性和/或跳动性感觉。由于NDPH似乎是最难治疗的头痛之一，因此需要进一步研究。
