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部分门静脉动脉化预防扩大胰胆手术后的大面积肝坏死:两例经验

Partial portal arterialization for the prevention of massive liver necrosis following extended pancreatobiliary surgery: experience of two cases.

作者信息

Iseki J, Touyama K, Noie T, Nakagami K, Takagi M, Hakamada K, Tanaka A, Yamada A, Hanakita J, Suwa H

机构信息

Department of Surgery, Shizuoka General Hospital, Japan.

出版信息

Surg Today. 1992;22(6):568-71. doi: 10.1007/BF00308907.

Abstract

Massive liver necrosis, which is a severe and highly fatal complication after extended pancreatobiliary surgery, may occur due to an interruption of the hepatic arterial flow caused by such events as an excision of the hepatic artery invaded by cancer, a ligation of the postoperatively ruptured hepatic artery, or a thrombotic obstruction of the reconstructed hepatic artery. In order to improve this ischemic state of the liver, we have performed a partial arterialization of the portal vein by making an arteriovenous shunt at the mesenteric vascular branches in two cases. Although a sufficient pathophysiological investigation could not be fully conducted, partial portal arterialization was considered to be effective in one patient, while no clinically noticeable adverse effects were revealed in the other patient.

摘要

大面积肝坏死是扩大胰胆管手术后一种严重且致死率很高的并发症,可能是由于诸如切除受癌侵犯的肝动脉、结扎术后破裂的肝动脉或重建肝动脉的血栓性阻塞等事件导致肝动脉血流中断所致。为改善肝脏的这种缺血状态,我们对两例患者在肠系膜血管分支处进行动静脉分流,从而实施了门静脉部分动脉化。尽管未能充分进行全面的病理生理学研究,但部分门静脉动脉化在一名患者中被认为是有效的,而在另一名患者中未发现明显的临床不良反应。

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